The Physical Activity and Weight Management Research Center at the University of Pittsburgh was established in 2002 under the direction of John M. Jakicic, Ph.D. This Center is part of the Department of Health and Physical Activity at the University of Pittsburgh. The mission of this Center is to conduct basic and applied scientific research related to the prevention and treatment of overweight and obesity, understand linkages between physical activity and physical fitness and health-related outcomes (i.e., physical, metabolic, cognitive, etc.) in adults and children. A primary emphasis of this research center is to examine the role of physical activity, exercise, and fitness on these health-related outcomes and to quantify the optimal dose of physical activity to maximize these outcomes. Moreover, the center engages in translational research to disseminate research findings to health-care, health-fitness, and community-based settings. The faculty and staff form a multi-disciplinary research team consisting of expertise in exercise, nutrition, and behavior modification. The primary source of research funding is the National Institutes of Health.